FederalDue May 7, 2027
National Institutes of Health
The purpose of the NIH Midcareer Investigator Award in Patient-Oriented Research (K24) is to provide support to mid-career health-professional doctorates for protected time to devote to patient-oriented research (POR) and to act as research mentors primarily for clinical residents, clinical fellows and/or junior clinical faculty.
Amount not specifiedOfficial notice ↗ FederalDue May 7, 2027
National Institutes of Health
The purpose of the NIH Midcareer Investigator Award in Patient-Oriented Research (K24) is to provide support to mid-career health-professional doctorates for protected time to devote to patient-oriented research (POR) and to act as research mentors primarily for clinical residents, clinical fellows and/or junior clinical faculty.
Amount not specifiedOfficial notice ↗ FederalDue May 7, 2027
National Institutes of Health
The purpose of the NIH Mentored Patient-Oriented Research Career Development Award (K23) is to support the career development of individuals with a clinical doctoral degree who have made a commitment to focus their research endeavors on patient-oriented research.
Amount not specifiedOfficial notice ↗ FederalDue May 7, 2027
National Institutes of Health
The purpose of the Mentored Quantitative Research Career Development Award (K25) is to attract to NIH-relevant research those investigators whose quantitative science and engineering research has thus far not been focused primarily on questions of health and disease. The K25 award will provide support and "protected time" for a period of supervised study and research for productive professionals with quantitative (e.g., mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry) and engineering backgrounds to integrate their expertise with NIH-relevant research.This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing to serve as the lead investigator of an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial, as part of their research and career development. Applicants not planning an independent clinical trial, or proposing to gain research experience in a clinical trial led by another investigator, must apply to companion FOA.
Amount not specifiedOfficial notice ↗ FederalDue May 7, 2027
National Institutes of Health
The purpose of the NIH Pathway to Independence Award (K99/R00) program is to increase and maintain a strong cohort of new and talented, NIH-supported, independent investigators. This program is designed to facilitate a timely transition of outstanding postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program will provide independent NIH research support during this transition in order to help awardees to launch competitive, independent research careers.
Amount not specifiedOfficial notice ↗ FederalDue May 7, 2027
National Institutes of Health
The purpose of the Mentored Quantitative Research Career Development Award (K25) is to attract to NIH-relevant research those investigators whose quantitative science and engineering research has thus far not been focused primarily on questions of health and disease. The K25 award will provide support and "protected time" for a period of supervised study and research for productive professionals with quantitative (e.g., mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry) and engineering backgrounds to integrate their expertise with NIH-relevant research.This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by a mentor or co-mentor. Applicants proposing a clinical trial or an ancillary clinical trial as lead investigator, should apply to the companion FOA ().
Amount not specifiedOfficial notice ↗ FederalDue May 8, 2027
National Institutes of Health
The purpose of the NIH Mentored Patient-Oriented Research Career Development Award (K23) is to support the career development of individuals with a clinical doctoral degree who have made a commitment to focus their research endeavors on patient-oriented research.
Amount not specifiedOfficial notice ↗ FederalDue May 8, 2027
National Institutes of Health
The primary purpose of the NIH Mentored Clinical Scientist Research Career Development Awards (K08) program is to prepare qualified individuals for careers that have a significant impact on the health-related research needs of the Nation. This program represents the continuation of a long-standing NIH program that provides support and "protected time" to individuals with a clinical doctoral degree for an intensive, supervised research career development experience in the fields of biomedical and behavioral research, including translational research.
Amount not specifiedOfficial notice ↗ FederalDue May 8, 2027
National Institutes of Health
The primary purpose of the NIH Mentored Clinical Scientist Research Career Development Awards (K08) program is to prepare qualified individuals for careers that have a significant impact on the health-related research needs of the Nation. This program represents the continuation of a long-standing NIH program that provides support and "protected time" to individuals with a clinical doctoral degree for an intensive, supervised research career development experience in the fields of biomedical and behavioral research, including translational research.
Amount not specifiedOfficial notice ↗ FederalDue May 31, 2027
Bureau of African Affairs
The U.S.-Africa Strategic Investment Program advances America's national interests by harnessing market-based, private sector-led growth across two strategic focus areas: Critical Minerals Investment and Commercial Diplomacy Acceleration. This program seeks market-based solutions that strengthen the environment for foreign investment in sub-Saharan Africa through transparent and competitive processes, creating sustainable economic growth in two strategic focus areas. Projects must demonstrate clear, measurable benefits to one or more sub-Saharan countries, such as increased investment from high-quality U.S. and U.S.-aligned companies. Applicants are also encouraged to identify how their projects create conditions that enable U.S. commercial participation.
$5,000,000 – $50,000,000Official notice ↗ CADue Jun 30, 2027
Department of Parks and Recreation
This grant provides resources for keeping boater sewage from California waterways.
The Pumpout Facility Grant Program funds the operation and maintenance of pumpout and dump stations on California's waterways.
Amount not specifiedOfficial notice ↗ CADue Jun 30, 2027
Department of Parks and Recreation
This grant provides resources for keeping boater sewage from California waterways.
The Pumpout Facility Grant Program funds the construction of pumpout and dump stations on California's waterways.
Amount not specifiedOfficial notice ↗ FederalDue Jul 12, 2027
National Institutes of Health
The National Institutes of Health (NIH) hereby notifies recipient organizations holding specific types of NIH grants, listed within the Activity Code section above, that applications for change of recipient organization may be submitted to this NOFO. This assumes such a change is programmatically permitted for the particular grant. Applications for change of recipient organization are considered prior approval requests (as described in Section 8.1.2.7 of the NIH Grants Policy Statement) and will be routed for consideration directly to the Grants Management Specialist named in the current award.
Although requests for change of recipient organization may be submitted through this NOFO, there is no guarantee that an award will be transferred to the new organization. All applicants are encouraged to discuss potential requests with the awarding IC before submission.
Amount not specifiedOfficial notice ↗ FederalDue Aug 18, 2027
National Institutes of Health
The Blueprint Neurotherapeutics Network for Biologics (BPN-Biologics) provides support for biologic-based therapeutic discovery and development, from lead optimization through phase I clinical testing. This Funding Opportunity Announcement (FOA) supports preclinical discovery and development of potential therapeutic Biotechnology Products and Biologics including, but not limited to, large biologic macromolecules, (e.g., proteins, antibodies, and peptides), gene-based therapies (i.e., oligonucleotide- and viral-based), cell therapies, and novel emerging therapies (e.g., microbial and microbiome therapies). Applicants will collaborate with NIH-funded consultants and can augment their project with NIH contract research organizations (CROs) that specialize in manufacturing, scaling, pharmacokinetics, toxicology, and Phase I clinical testing. BPN-Biologics awardee institutions retain their assignment of IP rights and gain assignment of IP rights from the BPN-Biologics contractors (and thereby control the patent prosecution and licensing negotiations) for biotherapeutic candidates developed in this program.
Amount not specifiedOfficial notice ↗ FederalDue Sep 8, 2027
Bureau of Reclamation
The objective of the WaterSMART Enhancing Water Resources Projects funding opportunity is to invite eligible entities to apply for funding to implement projects per the authorizing language referenced above that benefit water resource management for multiple uses, including water conservation and efficiency projects, water infrastructure improvements, and river and watershed restoration. Projects that balance numerous community interests (agriculture, recreation, fisheries, power, etc.), were developed collaboratively, and provide significant watershed benefits will be prioritized under this funding opportunity. This program demonstrably advances Trump administration priorities, such as those identified in Presidential Executive Order 14154 (January 20, 2025): Unleashing American Energy (E.O. 14154) and Secretarial Order 3418, and aligns with other priorities and requirements, such as those identified in Presidential Executive Order 14332 (August 7, 2025): Improving Oversight in Federal Grantmaking (E.O. 14332).
$50,000 – $3,000,000Official notice ↗ FederalDue Oct 25, 2027
National Institutes of Health
The purpose of the Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools is to support small scale research grants at institutions that do not receive substantial funding from the NIH, with an emphasis on providing biomedical research experiences primarily for health professional, undergraduate and graduate students and enhancing the research environment at applicant institutions.Eligible institutions must award baccalaureate or advanced science degrees and have received no more than $6 million dollars per year of NIH support (in both direct and F&A/indirect costs) in 4 of the last 7 fiscal years. For institutions composed of multiple schools and colleges, the $6 million funding limit is based on the amount of NIH funding received by all the schools and colleges within the institution as a whole.Help determining the Organization Funding Level can be found here or https://grants.nih.gov/grants/funding/r15.htmThis REAP Notice of Funding Opportunity (NOFO) supports investigator-initiated mechanistic and/or minimal risk clinical trials addressing the mission and research interests of the participating NIH institutes. For purposes of this NOFO, minimal risk clinical trials are defined as those that do not require FDA oversight, do not intend to formally establish efficacy, and have low risks to potentially cause physical or psychological harm.
FederalDue Dec 31, 2027
National Park Service
The National Park Service (NPS) are seeking applications for Master Cooperative Agreements from CESU network participants in the following CESU network regions:
North and West Alaska
Californian
Chesapeake Watershed
Colorado Plateau
Desert Southwest
Great Basin
Great Lakes Northern Forest
Great Plains
Great Rivers
Gulf Coast
Hawaii/Pacific Islands
North Atlantic Coast
Pacific Northwest
Piedmont-South Atlantic Coast
Rocky Mountains
South Florida Caribbean
Southern Appalachian
Cooperative agreements to CESU network participants residing in CESU network regions other than those listed above will be pursued separate from this notice of funding opportunity; however, those CESU network participants may still apply for a Master Cooperative Agreement under this announcement. Application instructions are found in Section D. Application and Submission Information.
Applications will be reviewed and evaluated as they are received and may be submitted at any time up until the closing date of this announcement.
The Cooperative Ecosystem Studies Units network is a national consortium of Federal agencies, tribes, academic institutions, state and local governments, nongovernmental conservation organizations, and other partners working together to support informed public trust resource stewardship. The CESU network includes 390 non-Federal partners and 15 Federal Agencies in seventeen (17) CESUs representing biogeographic regions encompassing all 50 states and U.S. territories. The CESU network is well positioned as a platform to support research, technical assistance, education and capacity building that is responsive to long-standing and contemporary science and resource management priorities.
The seventeen (17) CESUs bring together scientists, resource managers, students, and other conservation professionals, drawing upon expertise from across the biological, physical, social, cultural, and engineering disciplines (from Anthropology to Zoology) to conduct collaborative and interdisciplinary applied projects that address natural and cultural heritage resource issues at multiple scales and in an ecosystem context. Each CESU is structured as a working collaborative with participation from numerous Federal and non-Federal institutional partners. CESUs are based at host universities and focused on a particular biogeographic region of the country.
The NPS is required under “Research Mandate” 54 USC 100702 to ensure the management of NPS units are “enhanced by the availability and utilization of a broad program of the highest quality science and information.” To help answer this mandate, the NPS works cooperatively with approved CESU cooperators. Annually the NPS obligates between $30M and $40M in CESU cooperative agreements agency wide. Individual projects are up to five (5) years in duration with an average of approximately $60,000 per agreement.
The NPS plans to create Master Cooperative Agreements with CESU partners to carry out the CFDA program 15.945, Cooperative Research and Training Programs – Resources of the National Park System. The NPS is announcing the intent to solicit proposals from organizations within the CESU network. The objectives of the CESU program are:
a. Provide usable knowledge to support informed decision making.
b. Ensure the independence and objectivity of research.
c. Create and maintain effective partnerships among the Federal agencies and universities to share resources and expertise.
d. Take full advantage of university resources while benefiting faculty and students.
e. Encourage professional development of current and future Federal scientists, resource managers, and environmental leaders.
f. Manage Federal resources effectively.
Amount not specifiedOfficial notice ↗ FederalDue Jan 7, 2028
National Institutes of Health
The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.
Amount not specifiedOfficial notice ↗ FederalDue Jan 7, 2028
National Institutes of Health
The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s). The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.This Notice of Funding Opportunity does not accept applications proposing clinical trial(s).
Amount not specifiedOfficial notice ↗ FederalDue Jan 7, 2028
National Institutes of Health
The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. This Parent Notice of Funding Opportunity requires that at least 1 clinical trial be proposed. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.Applicants should note that some ICs (see Related Notices) only accept applications proposing mechanistic studies that meet NIH's definition of a clinical trial through this funding opportunity announcement.
Amount not specifiedOfficial notice ↗ FederalDue Jan 7, 2028
National Institutes of Health
The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s). This Parent Notice of Funding Opportunity Announcement requires that at lease 1 clinical trial be proposed. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.
Amount not specifiedOfficial notice ↗ FederalDue Jan 7, 2028
National Institutes of Health
The NIH Small Research Grant Program supports small research projects that can be carried out in a short period of time with limited resources. This program supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology.
This Notice of Funding Opportunity does not accept applications proposing clinical trial(s).
FederalDue Jan 7, 2028
National Institutes of Health
The purpose of this Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutionsis to support small scale research grants at institutions that do not receive substantial funding from the NIH, with an emphasis on providing biomedical research experiences primarily for undergraduate students, and enhancing the research environment at applicant institutions.
Eligible institutions must award baccalaureate science degrees and have received no more than $6 million dollars per year of NIH support (in both direct and F and A/indirect costs) in 4 of the last 7 fiscal years. For institutions composed of multiple schools and colleges, the $6 million funding limit is based on the amount of NIH funding received by all the non-health professional schools and colleges within the institution as a whole. See Part II. Section 3.1 Eligible Organizations for more information.
FederalDue Jan 7, 2028
National Institutes of Health
The purpose of the Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools is to stimulate basic and clinical research in educational institutions that provide baccalaureate or advanced degrees for a significant number of the Nation's research scientists, but that have not been major recipients of NIH support. REAP grants create opportunities for scientists and institutions otherwise unlikely to participate extensively in NIH research programs to contribute to the Nation's biomedical and behavioral research effort. REAP grants are intended to support small-scale research projects proposed by faculty members of eligible, domestic institutions, to expose undergraduate and/or graduate students at health professional schools or graduate schools to meritorious research projects, and to strengthen the research environment of the applicant institution.Eligible institutions must award NIH-relevant baccalaureate or advanced degrees in health professions and have received less than $6 million per year of NIH support (total costs) in 4 of the last 7 fiscal years. In this NOFO, a college is a stand-alone entity and not a component of a university system.